While I'm not Erich and have neither the criminal experience nor deadly force use experience I wouldn't use the 38spl with 110gr bullets either as a self defense bullet.

I have read a bit and I get my information from some FBI information when they tried that weight bullet in the 357Mag. It seemed to be the answer to their problem of more firepower until the auto glass started being reinforced with plastic, commonly known as safety glass.

It seemed that these "super bullets" would to one of two things when encountering either barrier. They either glanced off and went careening off to point unknown, something none of us can afford in a shooting, or splattered uselessly in the glass without penetrating it.

It would seem to me that that wasn't a very good tool to use to defend oneself. No, give me a heavy bullet going at moderate speeds, over 800fps at least.

IMO, the 40S&W with a 180gr bullet going just over 1000fps is the ticket. That's just me though!

YMMV