I tried some 2400 with good results a while back in the 357.
15.5grs of imr4227 should give me about 1200f/s ill load 5 rounds for comparison at aprox 1100f/s 14grs.
I will be shooting these out of a 66-1 4" barrel, not real sure what ths will give me for velocity. the reloading data is based on a 6" barrel
Dave