I own three 625s in .45 ACP and I shoot .45 Super equivalent handloads through them. Others on this forum shoot factory loaded .45 Super through theirs too without incident. I load the bullets slightly long so they won't chamber in my Glock 21s. Or I'll load 255 gr. bullets, which I consider the real advantage.
I believe that the .45 ACP is a far better choice than the .45 Colt in S&W revolvers. But if you're looking at the Ruger, then it's a different story.
Dave Sinko
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