Keep in mind, the .40 runs at much higher pressures than .45 ACP. As others have mentioned, powder as fast as Clays is not the best. When I shot a .40 as my Limited Class USPSA gun, I experimented with several powders, loading both 220 gr. cast bullets and 180 gr. FMJs. AA #5 worked well, and even Unique wasn't bad, but I like Viht N-340 best of the three.
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