Well, I just loaded 50 rounds of 180 gr. FMJ over 5.0 grains of Universal. The Lyman manual listed loads from 4.8 to 5.5. Hodgdon lists from 5.0 to 5.8 on their website. The 5 grains of Universal fills up the case to the point that while a double charge is possible, you'd have to insert a bullet with your eyes shut. 2X 5.8 would likely overflow the case.
I am using a Lee FCD to crimp the bullets and doubt there will be a setback problem. However, it's certainly something to keep an eye out for during load development.