I keep my 15/22 zero'd for 50 yards and its still right on at 50' and maybe a 1/2" high if that.
Ill put mine on the 100 yard range soon and then just move my vertical adjustment to make the required perfect poi at that range.
That way i only have to remember what 100 yards is on the dial as 50 yards is "0" and 50' is almost perfect at "0" also.
The best way to do this is keep the scope as close to the bore axis as possible.