One thing I have noticed with titegroup is that static electricity and high humidity can cause problems. Humidity can cause clumping and static electricity on plastic parts of powder measures/dispensers can cause powder to stick to the surfaces which will increase variability. I use my RCBS 1500 dispenser/balance to measure every charge. But then I do not shoot thousands of rounds a year, maybe 100-200 per month.

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Revolver luvin' Mountaineer