Yeah, the good colonel really hated the .25 ACP! I can't post his exact quote (Forum copyright rule) but he wrote about the subject in "Guns and Ammo". Cooper had no love for any small caliber handgun (and he considered the .380 to be in that category) but believed the .22 offered accuracy, no recoil to speak of, cheap ammunition for lots of practice, (3 things a small .380 didn't offer)and that it would penetrate a human skull not always but most of the time.

I for one believe he was right. I'd rather fight against someone armed with a .380 that they may run 50-100 rds through a year that someone with say an old Ruger .22 auto that they shoot 1500-2000 rds a year with.