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Looking at Hornady's manual for the 125 gr bullet, a load of 17.4 gr of H 110 is a starting load and 19.9 gr a max
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If case you haven't read the manufacturer's caution notes, H110/Win 296 are NOT suitable for experimenting and should be used strictly per instructions. These powders produce the maximum power, but can wear the gun faster..
The discussions above were with the assumption you were going to use powders more amenable to adjustment over a wide range. I load H110/296 loads for my 686, but I consider them hotter than what I want for my Model 66. Many medium powders produce mid-range .357 loads around 1000 to 1100 fps that are adequate for most purposes. Titegroup with 125gr jacketed bullet is less abusive than the H110.
The peak pressure is what blows up a gun, but a hot load also can accelerate wear without blowing it up.