I use my Little Dandy to load Unique, Bullseye and Trailboss. I have not had any problems. But when I set it up I do several things. One I make sure the powder tube is full. Second, I do ten powder dumps into a bowl to settle the powder. Then when working the rotor I give it two back clicks on each round. I do get a variation but it is very small.

I also weigh every 5th round to make sure it is on target or very close.

Lastly what powder chart are you using? My rotor 10 throws 5.2 of Unique and 9 throws 4.7.

I just loaded 50 round of 455 Webley last night with the #9 rotor. Getting 4.5 to 4.6 for every throw. I'm not an advanced reloader and only load several hundred rounds a month but I like the little dandy.