Id hafta say that the Pachymeyer grips are far and away more comfortable and would give you a little less fatigue. They are nothing to look at though, ugly rubber. I usually shoot Ahrends grips on my 44's. They feel a lot better and they arent checkered to irritate my hand.

Also, the 44 has a descent amount of recoil and you may just need some more shooting to condition your hand to the extra recoil.

Good luck and have fun.