Buffalo bore hard cast gas checked 180's, I've shot wild pigs in the head with these and they dropped like Thors hammer hit them. Out of a Dan Wesson 6 inch or 4 5/8 Blackhawk.

I'm of the opinion that any hollow point (regardless of maker) won't get the job done in a timely manner. You may have to adjust your sights for elevation so make sure you practice with any change in bullet weights.