This is an excellent read on the subject as I imagine it's been posted here before. Discussing various rounds on they perform once they enter the body. The author states flat out that he loves .45acp and .357 magnum as the best all around body droppers.
http://www.commonfolkusingcommonsens...n_a_morgue.pdf
Now as far as the subject at hand, which to use- specifically, which revolver or which .45. We can all agree it comes down to preference. I already have my preferred .45, an alloy framed commander, however I'm still looking for a seven shot alloy framed revolver with a combat length barrel and full length extractor. My suggestions to S&W went over like a ton of bricks as they do not offer, nor ever have offered a something as outlined earlier. The reps were suggesting the TRR8 but again for my preference, L frame alloy seven shot with full length extractor and combat length barrel would be max for carry.
Finally, I understand feeding any auto or revolver a steady diet of +P ammo isn't good. I just prefer to carry +P ammo when I can.
C77