Two entirely different rds. other than the fact they shoot the same diameter bullets. I have and use both but for different things. If I were to buy a new rifle today, I would probably skip the sevens and go to the 6.5's. Better bullet bc's and still capable of getting the job done , whether hunting or target shooting. In fact I am adding a 6.5 Creedmore to the battery in the near future and perhaps a 6.5/284 after that even tho it's a barrel burner.