I've discussed my use of my personal (cast bullet) handloads for defensive carry here many times, as well as my take as a lawyer on the legal issues that could accrue. Nutshell: I'm not concerned but I'm comfy in a courtroom; I gave my brother the same advice Mas gives and told him to carry factory loads.
All that aside, cast bullets are great for a lot of defensive purposes.
These bullets were a gift from our Mr. "Sacket"
And some from NKJ Nut's Tennessee Valley Bullets: