For carry, the 11oz scandium j frames.
If you plan to actually shoot it with serious defense loads...442 or 642.
I have all the above. The scandium guns are simply too light for plus p .38 or .357's. In your situation, as in most close-range defensive situations, the guy who shoots first, and gets a solid hit, usually wins. You have a better chance of accomplishing that with a J frame which can be fired from inside a jacket pocket if necessary, than with an autoloader. I'd consider the j frame my primary and for backup carry a 2nd j frame or an auto, though that would complicate your ammunition situation.