I have a 4" 16-4 and a 6" 16 no dash. Both are great shooters. You are probably going to spend $800-1000 for a nice 16-4 and about double that to get into a shooter model 16. I took the 16-4 to the range one day when I was going to shoot a couple .22 rifles. I set a few beer can targets out at 50 yards and hitting them with 16-4 was no problem. Next range trip I took the 16 and did the same thing.
One advantage to the 16-4 is you can shoot .32 H&R magnum in the gun and also have the chamber reamed to accept the .327 Federal magnum giving a little more flexibility.
I like the balance of the 4" full lug K frames but not so much with the 6" full lug guns. But that is my preference YMMV. They are great guns whichever you decide.