I load 240 gr JHP using H110 for full tilt stuff (23.8 gr), which is plenty hot and will cycle a Desert Eagle. I also load the same bullet with HS-6 (14.5 gr) which is comfortable in my wheel guns. The H110 is fun, but soots up the cases quite a bit. Have some test rounds loaded with Titegroup starting with 9.0 gr., hope to try them next time out.