The traditional conical lead bullet loadings from Winchester (255 grains) and Remington (250 grains) have a fairly soft lead bullet with a slightly concave base. They seem to slug up or down and shoot very well in a wide variety of .45 Colt revolvers with varying bore sizes and throat diameters. I find they shoot better for me in Colt and S&W revolvers than jacketed bullet commercial loads like W-W Silvertips or Federal 225 grain lead SWCs.

The 4 inch M-25-5 is probably the most popular because it is such a handy length, and the .45 Colt is a moderate pressure cartridge that doesn't need long barrels to develop their velocity. While a .357 or .44 Magnum is more pleasant to shoot with barrels of 6 inches or longer, the .45 Colt doesn't produce the same muzzle blast and racket the higher pressure Magnums do. 4 inch to 4-3/4 inch .45 Colt revolvers are still pleasant to shoot.