I guess it would be like how some people load their shotguns up with bird shot instead of buckshot to prevent over-penetration of walls. I still wouldn't want to get hit at close range with birdshot. It pretty much has the same impact. I also wouldn't want to get hit with 25 rounds of .22.
I'd use something like CCI Stingers (except in the PC model).
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686, 629, 15-22 MOE FDE
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