I have carried a SIG P229 for years and dispatched plenty of Deer and even a Moose with it...I have the .40 cal barrels for both of my personal 229/226 and the 155 grain is also a good round....165 is almost as good and the 180 is a round I would never carry on duty. I have fired thousands of 125 grain Gold Dots through my guns at all kinds of targets, windshields, car bodies and animals.....and never a failure of any kind. A fellow trainer who hunts with his Sig feels the Remington Golden Saber does a slightly better job on the Deer he kills. I have complete confidence that whatever I may face the .357 Sig will do the job and then some