I have a Vaquero with both cylinders. When I bought it used, the .45 ACP Cylinder was unused. It now has exactly 6 rounds through it. I agree with others here that the .45 Colt is a more accurate round in this gun.
I do not have any other revolvers that shoot .45 ACP, but I do have several pistols that do and they are almost as accurate as the Vaquero.
I have a .45 Colt 7 1/2" Blackhawk that is one of the most accurate guns that I own.
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Corripe Cervisiam
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