You will find that it works just fine. And you should be pleased with the accuracy of most any projectile.
Here is one of my 627s that has a second cylinder chambered for 9x23
The moonclips will hold had fire many cartridges
380ACP
9x17
9x19
9x21
9x21.5
356TSW
38ACP
38Super
9x23
etc.
now some of the brass may no longer be suitable for reloading, but it all functions.
The unfluted stainless cylinder is the one that came with the revolver. The black cylinder is a spare 357 Magnum cylinder that came from S&W and was converted by Pinnacle