I have large hands also and I have discovered the SIG autos fit me very well. I have found the SIG 220 fits me like a glove and I like it so well, I have three of them -- one in my truck, one next to the bed and the last one in the drawer by the couch.

I also have a .44 Cal. AutoMag pistol and a .45-70 revolver, both of which are large handguns and I find them comfortable to shoot.

__________________
Bill