I've use all the usual (see above) but started experimenting with IMR-4227.
Missouri Bullet Co. 240 coated bullets .430 BHN 12, Federal 150 primers, Starline brass, 15.5 grains of IMR 4227. Very accurate, unbelievably clean. Minimal powder residual, no leading very accurate. Gun is a Colt New frontier SAA with 5 1/2" barrel. Haven't had a chance to chrony it yet (battery was dead) but I'd guess around 850 ~900 fps