I don't do much +P, tending more towards 38spl and 357mag loads. Recently wringing out a nice 1953 Colt Officers Model with 4 cast bullets of 156-162 grains and 7 powders (WST,AA2,CFE,Bullseye,452AA,AA5 & 231) and the composite accuracy winner is AA5. My expectation is for 5 shots in 1" @ 50 feet.

From the 6" barrel, 5.6 grains AA5 averages ~850 fps and 5.8 grains gives ~900 fps. The standard deviations are a tad better at 900. The AA5 placed first and second with 158's and 125's, whereas WST was the opposite.

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Carry.."hope" isn't a strategy