For every one story you can show me where a safety got somebody hurt or
Killed during a self defense situation, I can find you 50 where a manual safety would have prevented an unnecessary injury or death. A woman was shot and killed by her 2 year old who got a hold of her Shield in a Walmart. It was in her purse and she had turned away. Yeah, she shouldn't have done that, but she's human and made a mistake. We all can.

The odds of any of us needing a gun in a self defense situation are astronomical. Odds are much better of an ND. Before Glock came along, millions of semi auto pistols with safeties were being carried and nobody felt like they were a liability.