All this 640 talk made me grab mine this morning. I though about my ammo strategy and decided to load 110grain 357 in the cylinder and speed strips with 125 grain +Ps in the speed loaders. I can always reload with the long nose 38s as fast as a 45 mag change. The longer 357 rounds take too much concentration and fiddling with the uncle Mike's combat grips. I want to hit them hard if needed. If I have time and cover I can use the speed strips which are equally fast with the long cartridges. If speed is of the essence then I go for the 38s.
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