Great link Irn-Bru, and yes shot placement trumps all, but close might still get you a cigar if your projectile delivers enough penetration and expansion in tissue and bone.

Like Muss I prefer Hornady Critical Defense with the FTX™ bullet in most of my defensive weapons. Critical Duty, as I understand it, provides more penetration and barrier shoot-through than Critical Defense rounds. Useful in Law Enforcement situations where shooting through windshields and car doors may be required.

These are my current carry loads:

.38 spcl ~ Hornady Critical Defense +p 110grn FTX (2' 340 Pro Series)
.38 spcl ~ Hornady Custom 158gr XTP (1 7/8" 360PD)

9mm ~ Hornady Critical Defense 115gr FTX (3.5" 39xx 59xx)

.40 S&W ~ Hornady Critical Defense 165gr FTX (4040PD)

.44 Mag ~ Hornady Critical Defense 225gr FTX (4" model 69)

.45 auto ~ Hornady 185gr XTP

Availability for this ammo is good in my area, pricing not so much.

digiroc