RPG is right. It doesn't make a tinkers d--m what's in your gun if it doesn't hit what you are aiming at. 1 hit with a 22 dead center is much better than an arm hit with a 357 at 1500 fps. I've seen a fair number of people shot. The quickest kill I saw in 25 years with the exception of a 12ga was with a 22 rifle. Girl friend shot him with a 22 rifle at 28ft. Had just "tuned her up". Had a cigarette in one hand, matches in the other and a smile on his face. DOF. ( dead on floor) Never knew what hit him. Accuracy beats big.