S&W originally made this pistol to compete for LE and MIL contracts. I really don't think they had Concealed Carry in mind when they made the new M&P.
As far as sanding why not try it on a grip that your not using or may never use and see how it handles the sanding.
Other than that I'll buy it from you for a $1.00.
Just so it doesn't irritate your skin.

LOL

I'm sure rubberized Talon grips will soon be available.