Some of the earlier 25's had throats that were oversized to .453 or even larger. Typical 45Colt bullets run .452. Check to see if you get a loose fit on a .452 size bullet. Some folks have even said that they slide right through the barrel (I've never seen that). If you do have an oversized throat, it's still not a show-stoppper, if you handload, use .454 or .455 resized bullets and all should be good.
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