For me, it depends on the frame size, and what I am shooting in it.
For example, I like Hogue Monogrips on my J-frame revolvers, particularly the Model 60s that get shot occasionally with .357 Magnum. I like them a bit less on my SP101, mostly because the grip gets a little too skinny down low - but then I like my SP101 less than my S&Ws anyway, so it kinda fits...
However, I've noted than the Hogue Monogrip on a K-frame interferes slightly with my HKS speed loaders. But that's not all bad as I really like the Pachmayr Compact grips on my K-frame sized .357 magnums. It's comfortable to shoot, but still small enough to be easily concealed with an IWB holster. I also like the same grip on my Ruger Speed Six.
When it comes to my 6" Model 19, my 4" Model 15, and my recently acquired 6" Model 66, I despise them both and prefer the S&W wood target stocks. They are perfect for .38 Special target loads, and work fine for the occasional .357 Mag in a 19 or 66, and they look a whole lot better than any rubber grip.