There are complications to rebuilding it. Cylinders, side plates and yokes are fitted to frames after which the barrel is fitted. The odds are good that a random yoke would not work or the barrel would have to be set back to meet up with a random cylinder. There is a good chance that a used side plate will leave gaps around its edge where it was shaved to fit a different frame. Also very few gunsmiths have experience fitting side plates.

A local gunsmith has a late pre-war stripped N frame that for the last 50 years he has talked about building into a .45 Colt. Some how it's never gotten built.