All that you would risk.....
All that you would risk would be a misfeed....maybe. If both loads are at the same power level recoil should be about the same. i.e. The light bullet going faster and the heavier bullet going slower. They may 'feel' a tad different, but unless you have a large difference in power level I doubt that it would be much.
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"He was kinda funny lookin'"
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