One time-saver that's available with a single-stage is the Lock n Load system from Hornady. Many of the newer presses are threaded for the larger 50-cal. type dies, and use a bushing system to reduce to the standard 7/8/14 dies. Hornady offers a bushing that receives the smaller dies with a twist-lock system with a twist-lock attachment attached to each die, so it only needs to be adjusted once within its bushing. The system can be used with modern single-stage presses from Hornady, RCBS, Redding, Lyman and others. You can change dies or calibers in a couple of seconds.