I've carried a .380 backup gun and occasionally as a concealed carry gun when the threat situation was low but I wanted to carry something small. I have since retired the 380 PPKs and replaced with a 9mm Ruger LC9s which gives me a similar sized but lighter package with a better round.
I've only had to use a .380 one time in a threat situation and it fared quite well with Federal Hydra-Shoks.