My progressive experience is just a few weeks and around 500-800 rounds of 357 Magnum, 45 ACP and 44 Magnum.

I have never liked priming on a press and thus have been priming with a hand primer. To my surprise the Dillon RL550B priming works smoothly and provides pretty good feedback. This is especially noticeable with 45 ACP where I have reloaded a mix of different cases and they have different primer pockets, including crimped ones. I can feel when there is trouble seating a primer fully.

Now I am looking at a Hornady LnL AP and/or Dillon XL650, mostly out of curiosity. The RL550B is already very nice, and the manual indexing is not a problem at all.

I load 100-500 rounds at a time so a super high production rate is not all that important to me.