I am going to go with gunsmith Dave Ciccionies advice and say no to smokeless of any sort. I load .38 and .32 S & W with black powder, or bp substitutes. Fill with 3fg until you get about 1/16" compression, i think it's about 13 grns for the .38's. Nice, low pressure, but with good power. I shoot LRN's, but if you can get a semiwadcutter or something, it would probably be a better defensive round. The LRN mold is what i have