I guess we're talking primarily of cast bullet use here. Just as something to consider, we often make more work than necessary in achieving a goal.
Years back, I did some cast bullet experimentation using grease wads, both the commercial variety and home-made using a Cabine Tree extruder pump. While I actually had some success, I proved to myself that a bullet of the proper alloy and fit negated the need for grease wads altogether.
My work with fillers has been more limited and I haven't used them in a long time, but it seems fillers are similar to grease wads as far as their degree of usefulness goes. They work and may work very well, but using the right powder with a fitted bullet of proper alloy will negate the need for a filler.
These are generalized comments. We all know there are exceptions, always.
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