I have an awful lot of handguns, but this is what I mostly carry:
A 340 PD, with a Galco horsehide pocket holster, and loaded with Speer 357 magnum short barrel 135 gr. Gold Dots.
I feel confident with it, and loaded in the holster, weight is just under 16 ounces. With me constantly, unless I feel like carrying something else just for variety.
Best Regards, Les