Originally Posted by Ray1970

I would never argue with someone about their choice of caliber and I fully understand that sometimes physical factors can play a major role in things. However, I did want to toss out the main problem that I would have relying on a 22LR for self defense. My main issue is with ignition reliability in a rim fire cartridge. I'm sure we've all been at the range having fun going through a large box of 22's. Inevitably, a few of those rounds just won't fire- not even after several attempts. I just wouldn't trust that the round I might have to fire to save my life wouldn't be one of those "duds".

I will add that if carrying something chambered in 22LR was my only option then I think I would definitely carry a revolver. If that first round doesn't fire, at least a quick second pull of the trigger gets me a fresh round.