I like Hydra-Shok, and a Federal PR man told me that it works well on deer at ranges at which one should be shooting a .357 at a deer. I think it's also a good defense round, and I don't shoot light bullets in most .357's.

Jimmy J mentioned the Winchester 145 grain ST. It was FBI issue and used by Dallas PD. A detective in a Dallas suburb checked autopsy results where felons were shot with that load, and he said that it was almost too effective! But he's a sensitive lad. If it kills effectively, I don't mind that it tore up a thug.

BTW, that's one of the best .357 loads in a three-inch barrel, giving about 1200 FPS. A bit too much in a SP-101 or J-frame .357. In those, I'd use Speer's Short barrel 135 grain load.

I used to fire Remington's 158 grain JHP and JSP from a Model 27 with exceptional accuracy, but now tend to avoid anything by Remington.