I definitely prefer IWB. The few times I've used OWB it kept feeling like the gun was pulling away from my body, and that's with a good quality holster and gun belt. IWB feels more secure. Plus, I don't have to worry about the bottom of my holster being exposed if I'm out and about and have to reach up to get something or if a gust of wind blows up the bottom of my shirt. At this point, I see no reason to get an OWB holster, unless I end up taking a training course that prohibits IWB carry.

My experience with holsters have all been with leather, and that's my preference. I can definitely see some advantages with kydex, though. I'm sure at some point I will try a kydex holster. My speedloader pouches, made by JOX, are kydex and are the best speedloader pouches I've tried.