Yes, I have experienced almost exactly that... I was shooting my Ruger 22/45 LITE with American Eagle 40gr ammo. It seemed a portion of the box was either spotty or no lube on the bullets. It leaded the barrel up quite quickly. I cleaned the barrel and got slivers of lead on the initial patches. After a quick thorough cleaning and switching to a better brand shooting went back to normal. I used a spray lube on that box of bullets and used them up on the next trip to the range in a different firearm.

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John