I by far am not informed of the tech side of each round. But, I have a step son that thought his wife would be better if he were dead. He sat on the sofa about 15 feet away, she shot him with a .22 LONG RIFLE. He had one collapsed lung, one big chunk of lead stopped under the shoulder blade skin. Oh, she shot him in the chest. He spent 2 days in intensive care, 3 more days in step down intensive care, one day in routine care. This happened in 2006. His wife died of o/dose in 2016. He still says he loved her. DUMBASS!!! Anyway, he still has problems breathing, muscles in chest. I only carry .38 caliber, Hornady Critical. I never feel under gunned. Just my 2 cents about a real life incident. Happy shootin and always be safe!