An antique gun can be sold to anyone anywhere without any restrictions, except maybe in New York, California, and maybe another state or two. An antique 38 Double Action must have a serial number at or below serial #382,022. By BATF definitions, an antique gun is not considered a firearm.

Any "modern" 38 DA will need the assistance of an FFL or a C&R-FFL to sell or transfer interstate as Guy states. Some states have additional requirements for the sale of a modern handgun as well, while other states require registration of handguns. If you do not live in one of those states and don't intend to sell it across state lines, no difference between antique and modern handgun definition for you. It was generally thought that antique status is more valuable then the same model made after 1898, but I am not so sure that is the case today.

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Gary
SWCA 2515