A few years back I built the following loads for my Charter Arms Bulldog:

4.5 grains of 700-X under a Matt's 250 grain cast hollowpoint (designed to expand at slow speeds). This recorded 693 fps average for 267 fpe.

A more potent load was 9.5 grains of Blue Dot under the same Matt's 250 grain cast HP for an average of 799 fps for 354 fpe (.45 Auto power). And yes, those BD loads are "hot" but would be my carry choice for SD or animal carry.

I know what the Charter is "rated" to handle, and for general range plinking I'd stay with a much lighter slug in the 160-180 grain range pushed around 700 fps.