Like others have said. I always clean and lube a new pistol before shooting, and then every time after shooting.

I don’t think there’s a break in period necessarily. For a carry gun I shoot a minimum of 500 rounds of ball ammo and 50-100 rounds of my carry ammo. If there are no failures and I feel 100% comfortable that I can run it under stress, then it goes into the rotation. If I’m not 100%, then I shoot more rounds until I am.