IIRC the original purpose-driven S&W road pistol came out in in 1935 on an N frame with a 6" or so barrel loaded with 158 grain pointed, metal-piercing .357 ammo.
It's direct descendant and 24 rounds of similar ammo live in my road trip bag.
I know six rounds at a time may seem like a disadvantage but that is how I trained and I wouldn't trade a bottomless magazine for the familiarity or the penetration.
Just 1/50th of a dollar's worth. JD
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On the whistle draw and fire 6
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